It's a well known fact that you're not playing a LucasArts game unless there's some reference to Star Wars or Sam & Max occuring at some point. They also have a tendency to feature supporting roles in some games. For instance -
Sam & Max Hit the Road has a guest appearance by Bernard from Day of the Tentacle as a Snuckey's clerk.
Full Throttle - is that George Lucas himself waving to the crowd before the demolition derby?
And finally, how many times has the seagull from Loom appeared in the Monkey Island series?
Anyone else spotted other cameo roles in other games?
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A pirate I was meant to be,
Trim the sails and roam the sea!
i think jumbeax le feet is the same voice as Glottis from Grimfandango
Manny makes a cameo in CMI
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Rage. What better time than now?